The chapel where popes are elected, its ceiling Michelangelo’s Genesis; next door, Raphael’s ancient Greek philosophers gather in one room.

A man who called himself a sculptor was forced by the pope to paint the ceiling on his back for four years.
Michelangelo always held himself a sculptor, not a painter, yet Pope Julius II ordered him to paint the Sistine ceiling. He painted it for four years on his back on the scaffolding, giving us the almost-touching fingertips of The Creation of Adam. More than twenty years later he returned to paint The Last Judgment on the altar wall. An unwilling sculptor left the greatest ceiling in the history of Western painting.
Sources:Vasari, Lives of the Artists · The letters of Michelangelo
↑ Because of the last layer:The same Pope Julius II hired both Michelangelo and Raphael at once, setting these two walls in dialogue across the space.
A few steps away, in the Stanza, Raphael painted Plato, Aristotle, and Socrates into one grand hall.
At the same time as the Sistine, a few steps away in the papal Stanza della Segnatura, Raphael painted The School of Athens: Plato pointing up, Aristotle pointing down, with Socrates, Pythagoras, Diogenes, and Euclid all present — dozens of ancient Greek philosophers gathered under one grand vault. The painting is itself the "philosophy universe" set on a wall by a Renaissance painter — standing here, you see at once both art and the whole history of ancient Greek thought.
Sources:Vasari, Lives of the Artists · The frescoes of the Stanza della Segnatura, Vatican
To this day the world’s cardinals still elect a new pope, sealed beneath this ceiling.
The Sistine is not only a gallery — it is a living center of religion. When a pope dies, the world’s cardinals gather here in sealed conclave, voting beneath Michelangelo’s Last Judgment until white smoke rises from the chimney to announce a new pope. The greatest room in art history is at the same time the scene where power passes for a billion believers.
Sources:Rules governing the papal conclave
In Rome:Michelangelo finishes the Sistine ceiling.
At the same time, elsewhere:At the same time, Magellan was about to set out to circle the globe, and Ming China was in the Zhengde reign.
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